TAttah E B, Ekere M C
JAMA. 1975 Aug 25;233(8):889-90. doi: 10.1001/jama.233.8.889.
In Ibadan, Nigeria, 28 patients with sickle cell disease (hemoglobin SS and SC) died and were autopsied. Fifty percent of these had died by the age of 5 years, as did 21 (68%) with homozygous hemoglobin SS disease. No death occurred in infancy or childhood among the patients with hemoglobin SC disease. Serious intercurrent disease that could have been responsible for death was present in ten patients (36%). The type and frequency of intercurrent disease appears to be related to the environment.
在尼日利亚伊巴丹，28例镰状细胞病（血红蛋白SS型和SC型）患者死亡并接受了尸检。其中50%在5岁前死亡，21例（68%）纯合子血红蛋白SS病患者也是如此。血红蛋白SC病患者在婴儿期或儿童期均未死亡。10例患者（36%）存在可能导致死亡的严重并发疾病。并发疾病的类型和频率似乎与环境有关。
