Schneider L S, Tariot P N, Lyketsos C G, Dagerman K S, Davis K L, Davis S, Hsiao J K, Jeste D V, Katz I R, Olin J T, Pollock B G, Rabins P V, Rosenheck R A, Small G W, Lebowitz B, Lieberman J A
Clinical Antipsychotic Trials of Intervention Effectiveness Program of the National Institute of Mental Health at the University of North Carolina, Chapel Hill, NC, USA.
Am J Geriatr Psychiatry. 2001 Fall;9(4):346-60.
The authors describe the development of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) protocol for Alzheimer disease (AD), a trial developed in collaboration with the National Institute of Mental Health (NIMH), assessing the effectiveness of atypical antipsychotics for psychosis and agitation occurring in AD outpatients. They provide an overview of the methodology utilized in the trial as well as the clinical-outcomes and effectiveness measures that were implemented.
作者描述了阿尔茨海默病（AD）临床抗精神病药物干预有效性试验（CATIE）方案的制定情况，该试验是与美国国立精神卫生研究所（NIMH）合作开展的，旨在评估非典型抗精神病药物对AD门诊患者出现的精神病和激越症状的疗效。他们概述了试验中使用的方法以及所实施的临床结果和有效性测量指标。
