Ruggerini R, Mazzocchi F, Albini G, Cifalinò M
Minerva Anestesiol. 1979 Sep;45(9):687-90.
Intravenous administration of 400-600 mg/day potassium canrenoate normalised plasma osmolarity and permitted rapid re-establishment of the metabolic picture in 9/12 patients with hyperosmolarity admitted to a resuscitation department for complex physiopathological pictures. The soundness of the drug in this sense is affirmed, as well as its permission of the recommencement of parenteral nutrition.
对于因复杂生理病理状况而入住复苏科的12名高渗患者中的9名,静脉注射400 - 600毫克/天的钾环孢素可使血浆渗透压正常化,并能迅速恢复代谢状态。从这个意义上来说,该药物的安全性得到了确认,并且也允许重新开始肠外营养。