Eschner J, Fodor L, Ahnefeld F W
Infusionsther Klin Ernahr. 1976 Apr;3(2):98-104.
In 61 patients the influence of canrenoate potassium on the shift of electrolytes during the intraoperative phase is studied. Without medication of canrenoate potassium depletion of potassium, magnesium and zinc occurs, a sign of transitory intraoperative hyperaldosteronism. On the other hand, preoperative and intraoperative infusion of 1000 mg canrenoate potassium prevents an increased excretion of electrolytes. Causes and consequences of the electrolyte depletion as well as the effect of canrenoate-potassium medication are discussed.
对61例患者研究了坎利酸钾在手术期对电解质变化的影响。未使用坎利酸钾时,会出现钾、镁和锌的缺失,这是术中暂时性醛固酮增多症的表现。另一方面,术前和术中输注1000毫克坎利酸钾可防止电解质排泄增加。文中讨论了电解质缺失的原因和后果以及坎利酸钾用药的效果。