Cristodorescu R, Puschita M, Deutsch G, Berger E, Luca C
Med Interne. 1977 Jan-Mar;15(1):27-34.
In 16 patients with critical condition due to severe heart failure associated with digitalis toxicity, the effects of potassium canrenoate (AldactoneR) administered intravenously were studied. Rhythm and conduction disturbances disappeared or improved in all instances. This effect was well correlated with an increase of serum potassium concentration. In 13 patients, after 1-2 days of Aldactone therapy, heart failure improved, which could be explained by a diuretic effect and by a possible inotropic action of aldactone. It is concluded that intravenous Aldactone is useful in patients with severe heart failure and digitalis toxicity in whom diuretics are often ineffective and even dangerous.
对16例因严重心力衰竭合并洋地黄中毒而病情危急的患者，研究了静脉注射螺内酯（安体舒通）的效果。所有病例的节律和传导紊乱均消失或改善。这种效果与血清钾浓度的升高密切相关。13例患者在接受螺内酯治疗1 - 2天后，心力衰竭得到改善，这可能是由于利尿作用以及螺内酯可能的正性肌力作用。得出结论，静脉注射螺内酯对重度心力衰竭合并洋地黄中毒的患者有用，这类患者使用利尿剂往往无效甚至危险。
