Zhang N, Pan L, Dai J, Wang B, Wang E, Zhang W, Cai P
Department of Neurosurgery, Hua Shan Hospital & Shanghai Gamma Knife Hospital, Shanghai, China.
Stereotact Funct Neurosurg. 2000;75(2-3):123-8. doi: 10.1159/000048393.
To estimate the efficacy of Gamma Knife radiosurgery (GKR) especially as a primary surgical treatment for hypersecreting pituitary adenomas.
274 patients were treated with GKR. The mean tumor volume was 1.86 cm(3). The mean peripheral dose was 28.7 Gy.
223 patients were followed up for an average of 31.6 months. The dose related to the tumor growth control and endocrinological normalization was detailed and statistical analysis of the data was performed.
GKR as a primary surgical treatment for hypersecreting pituitary adenomas may be safe and effective.
评估伽玛刀放射外科治疗（GKR），尤其是作为分泌过多型垂体腺瘤的主要外科治疗方法的疗效。
274例患者接受了伽玛刀放射外科治疗。平均肿瘤体积为1.86立方厘米。平均周边剂量为28.7 Gy。
223例患者接受了平均31.6个月的随访。详细记录了与肿瘤生长控制和内分泌功能恢复正常相关的剂量，并对数据进行了统计分析。
伽玛刀放射外科治疗作为分泌过多型垂体腺瘤的主要外科治疗方法可能是安全有效的。
