[水飞蓟宾和双水飞蓟宾的抗鬼笔环肽活性]
[Anti-phalloidine activity of the silymarins silybine and disilybine].
作者信息
Vogel V G, Trost W
出版信息
Arzneimittelforschung. 1975 Mar;25(3):392-3.
PMID:1174039
Abstract
Originating from silybin, a phenylchromanone from Silybum marianum (L.) Gaertn., a dimer -- disilybin -- was prepared. Disilybin exhibits a phalloidin antagonistic activity at least 10 times that of silybin with regards to a dose of the same weight.
摘要
水飞蓟宾是水飞蓟（Silybum marianum (L.) Gaertn.）中的一种苯基色原酮，基于水飞蓟宾制备了一种二聚体——双水飞蓟宾。就相同重量剂量而言，双水飞蓟宾表现出的鬼笔环肽拮抗活性至少是水飞蓟宾的10倍。
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