Jackson F R, Schroeder A J
Department of Neuroscience, Tufts University School of Medicine, 136 Harrison Avenue, Boston, MA 02111, USA.
Dev Cell. 2001 Dec;1(6):730-1. doi: 10.1016/s1534-5807(01)00100-9.
Molecular genetic analysis has yielded a detailed mechanistic understanding of invertebrate and vertebrate circadian oscillators, but we still know little about how such molecular oscillators are connected to rhythmic physiological processes. Two recent papers in Cell and Neuron now address this scientific issue through the use of gene chip technology to identify clock-regulated genes in an animal species.
分子遗传学分析已使我们对无脊椎动物和脊椎动物的昼夜节律振荡器有了详细的机制性理解,但我们对这些分子振荡器如何与节律性生理过程相联系仍知之甚少。《细胞》和《神经元》杂志最近发表的两篇论文,通过利用基因芯片技术来识别一种动物物种中受生物钟调节的基因,探讨了这一科学问题。