术前静脉营养——一项对照试验。
Pre-operative intravenous feeding--a controlled trial.
作者信息
Heatley R V, Williams R H, Lewis M H
出版信息
Postgrad Med J. 1979 Sep;55(646):541-5. doi: 10.1136/pgmj.55.646.541.
Abstract
Seventy-four patients with a pre-operative diagnosis of stomach or oesophageal cancer were entered into a randomized, controlled clinical trial to assess the value of a short course of pre-operative intravenous nutrition. The effectiveness of this treatment was assessed by the clinical course and monitored by means of immune and biochemical profiles. Pre-operative parenteral nutrition given over a 7-10-day period resulted in a significant reduction in the incidence of postoperative wound infections. Clinical benefit was confined to those patients who had a low serum albumin on admission to hospital. It is doubtful whether this limited benefit justifies the routine use of intravenous feeding, with its attendant hazards, in the pre-operative preparation of patients with upper gastrointestinal cancer.
摘要
74例术前诊断为胃癌或食管癌的患者进入一项随机对照临床试验，以评估术前短期静脉营养的价值。通过临床病程评估该治疗的有效性，并通过免疫和生化指标进行监测。术前7 - 10天给予肠外营养可显著降低术后伤口感染的发生率。临床获益仅限于入院时血清白蛋白水平较低的患者。对于上消化道癌患者的术前准备，这种有限的获益是否足以证明常规使用静脉喂养及其伴随的风险，尚值得怀疑。
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