口服蛋氨酸负荷作为急性血清叶酸缺乏的一个原因：其与肠外营养的相关性。
Oral methionine loading as a cause of acute serum folate deficiency: its relevance to parenteral nutrition.
作者信息
Connor H, Newton D J, Preston F E, Woods H F
出版信息
Postgrad Med J. 1978 May;54(631):318-20. doi: 10.1136/pgmj.54.631.318.
Abstract
Oral methionine supplements (8.0 g daily for 4 days) were given to five normal volunteers who continued to eat their usual diet. This treatment resulted in a significant fall in serum folate concentration. Three days after the end of treatment concentrations had not completely returned to control values. The fall in concentration was prevented by giving oral folic acid supplements. It is suggested that folic acid supplements should be given to patients who are receiving intravenous infusions of amino acid mixtures.
摘要
给五名正常志愿者口服蛋氨酸补充剂（每日8.0克，共4天），这些志愿者继续保持日常饮食。这种治疗导致血清叶酸浓度显著下降。治疗结束三天后，浓度尚未完全恢复到对照值。口服叶酸补充剂可防止浓度下降。建议对接受静脉输注氨基酸混合物的患者补充叶酸。
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