Harington J S, McGlashan N D, Bradshaw E, Geddes E W, Purves L R
Br J Cancer. 1975 Jun;31(6):665-78. doi: 10.1038/bjc.1975.114.
The pattern of cancer in African gold miners over the 8-year period 1964-71, comprising 2,926,461 man-years of employment was studied. Of the 1344 cancers found, primary liver cancer accounted for 52-8%, oesophageal cancer 12-1%, cancer of the respiratory system 5-4% and cancer of the bladder 4-8%. Analysis of the spatial distribution of these four cancers, both on subcontinental and local scale, showed distinct gradients of occurrence between areas of significantly higher and lower incidence than expected. In the case of primary liver cancer in Mozambique and oesophageal cancer in the Transkei, the spatial distribution reflects closely that found in the general resident population of each territory. The crude incidence rate of primary liver cancer in gold miners from Mozambique dropped sharply over the period of the survey.
对1964年至1971年这8年期间非洲金矿工人的癌症发病模式进行了研究，这些工人的总就业人年数为2926461人年。在发现的1344例癌症中，原发性肝癌占52.8%，食管癌占12.1%，呼吸系统癌症占5.4%，膀胱癌占4.8%。对这四种癌症在次大陆和局部尺度上的空间分布分析表明，在发病率显著高于和低于预期的地区之间存在明显的发病梯度。就莫桑比克的原发性肝癌和特兰斯凯的食管癌而言，空间分布与每个地区普通居民中的情况密切相关。在调查期间，莫桑比克金矿工人原发性肝癌的粗发病率急剧下降。
