Gürol M E, Ertas M, Hanagasi H A, Sahin H A, Gürsoy G, Emre M
Department of Neurology, Istanbul School of Medicine, University of Istanbul, Istanbul, Turkey.
Mov Disord. 2001 Nov;16(6):1189-93. doi: 10.1002/mds.1224.
We report on a 28-year-old woman with insulin-resistant diabetes mellitus with a 5-year history of progressive stiffness and painful spasms of the right leg, exaggerated by sudden auditory and tactile stimuli or by emotional stress. There were no signs of truncal rigidity or exaggerated lumbar lordosis. Anti-glutamic acid decarboxylase antibodies were positive in her serum. She improved substantially with clonazepam 4 mg/day. She presented with electrophysiological findings not previously reported in stiff leg syndrome, which may suggest increased inhibition in the uninvolved upper extremities.
我们报告了一名28岁患有胰岛素抵抗型糖尿病的女性,她有5年右腿进行性僵硬和疼痛性痉挛的病史,突然的听觉和触觉刺激或情绪压力会使其加重。没有躯干僵硬或腰椎前凸加剧的迹象。她的血清中抗谷氨酸脱羧酶抗体呈阳性。她服用4毫克/天的氯硝西泮后有显著改善。她出现了僵硬腿综合征中以前未报道过的电生理结果,这可能表明未受累的上肢抑制作用增强。