Aminocaproic acid and menstrual loss in women using intrauterine devices.

A controlled study of the effect of aminocaproic acid 3 g six-hourly taken by mouth during menstruation was carried out on 56 women for eight months from the time of insertion of a Lippes D intrauterine device (IUD). Thirty-five women presenting with menorrhagia in association with an IUD were also treated during three out of six consecutive menses. A highly significant reduction in menstrual loss was observed during treatment in both groups.