Sinclair Neil, Assaad Nazih, Johnston Ian
Department of Neurosurgery, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
J Clin Neurosci. 2002 Jan;9(1):99-101. doi: 10.1054/jocn.2000.0947.
Summary The case is described of a 12-year-old girl presenting with raised intracranial pressure without ventricular dilatation and a type 1 Chiari malformation. This was taken to be a coincidental association of pseudotumour cerebri and the Chiari malformation. Treatment of the pseudotumour with Diamox gave rapid and sustained relief of the intracranial hypertension without change in the Chiari malformation. In addition, a series of 156 cases of pseudotumour cerebri was reviewed for evidence of the Chiari malf ormation. An overall incidence of 1.3%, rising to 2.7% in patients with MR scanning [excluding the case described] was found.
摘要 本文描述了一名12岁女孩的病例，该女孩表现为颅内压升高但无脑室扩张，以及1型Chiari畸形。这被认为是假性脑瘤与Chiari畸形的巧合关联。用醋甲唑胺治疗假性脑瘤可迅速且持续缓解颅内高压，而Chiari畸形无变化。此外，回顾了156例假性脑瘤病例以寻找Chiari畸形的证据。发现总体发生率为1.3%，在进行磁共振扫描的患者中（不包括所描述的病例）升至2.7%。
