De Toledo S, Bozzo L, Do Nascimento A, Sallum A W
Rev Bras Pesqui Med Biol. 1979 Jun;12(2-3):141-6.
Adult marmosets of both sexes, weighing about 300 grams received intraperitoneal injections of 1.5 mCi of I131. Alterations in periodontal and thyroid gland tissues were determined 30, 45, 60 and 90 days after the administration, using the histological method. In the thyroid gland, degeneration and necrosis of the follicles and absence of the colloid substance with later substitution of the glandular tissue by a cicatricial fibrous tissue were observed. In the periodontium changes occurred in the alveolar bone, followed by degeneration of the periodontal ligament with areas of hyalinization from 30 days period up to the conclusion of the experiment. The cementum and the dentine were the last structures to present evidences of degeneration, showing areas of resorption only in the 60 and 90 days periods.
体重约300克的成年雌雄狨猴接受了1.5毫居里的I131腹腔注射。给药后30、45、60和90天，采用组织学方法测定牙周组织和甲状腺组织的变化。在甲状腺中，观察到滤泡变性和坏死，胶体物质缺失，随后腺组织被瘢痕性纤维组织替代。在牙周组织中，牙槽骨发生变化，随后牙周膜变性，从第30天到实验结束出现玻璃样变区域。牙骨质和牙本质是最后出现退变迹象的结构，仅在60天和90天期间出现吸收区域。
