Kreppel Lisa, Kimmel Alan R
Laboratory of Cellular and Developmental Biology (50/3351), National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-8028, USA.
Nucleic Acids Res. 2002 Jan 1;30(1):84-6. doi: 10.1093/nar/30.1.84.
Dictyostelium is an attractive model system for the study of mechanisms basic to cellular function or complex multicellular developmental processes. Recent advances in Dictyostelium genomics have generated a wide spectrum of resources. However, much of the current genomic sequence information is still not currently available through GenBank or related databases. Thus, many investigators are unaware that extensive sequence data from Dictyostelium has been compiled, or of its availability and access. Here, we discuss progress in Dictyostelium genomics and gene annotation, and highlight the primary portals for sequence access, manipulation and analysis (http://genome.imb-jena.de/dictyostelium/; http://dictygenome.bcm.tmc.edu/; http://www.sanger. ac.uk/Projects/D_discoideum/; http://www.csm.biol. tsukuba.ac.jp/cDNAproject.html).
盘基网柄菌是研究细胞功能基础机制或复杂多细胞发育过程的一个有吸引力的模型系统。盘基网柄菌基因组学的最新进展产生了广泛的资源。然而,目前许多基因组序列信息仍无法通过GenBank或相关数据库获取。因此,许多研究人员并不知道已经汇编了来自盘基网柄菌的大量序列数据,也不知道其可用性和获取途径。在这里,我们讨论盘基网柄菌基因组学和基因注释方面的进展,并重点介绍序列访问、操作和分析的主要入口(http://genome.imb-jena.de/dictyostelium/;http://dictygenome.bcm.tmc.edu/;http://www.sanger.ac.uk/Projects/D_discoideum/;http://www.csm.biol.tsukuba.ac.jp/cDNAproject.html)。