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经胸超声心动图评估主动脉瓣狭窄的严重程度

Cross-sectional echocardiography in assessing the severity of valvular aortic stenosis.

作者信息

Weyman A E, Feigebaum H, Dillon J C, Chang S

出版信息

Circulation. 1975 Nov;52(5):828-34. doi: 10.1161/01.cir.52.5.828.

Abstract

Real-time, cross-sectional echocardiograms were recorded in 28 consecutive adult patients with valvular aortic stenosis using a high resolution, mechanical sector scanner. Using the cross-sectional technique, the aortic valve orifice diameter was recorded in each of the 28 patients. With M-mode echocardiographic examination of these same patients, this value could be estimated in only 21 of these 28 patients (75%). The maximum aortic valve diameter recorded during the cross-sectional study averaged 7.9 +/- 1.8 mm (range 4-11 mm) in 15 patients with severe aortic stenosis; 11.6 +/- 2.3 mm (range 9-15 mm) in five patients with moderate aortic stenosis; 16.9 +/- 2.0 mm (range 14-20 mm) in eight patients with mild aortic stenosis; and 20.5 +/- 2.8 mm (range 15-26 mm) in 25 patients with no evidence of aortic valve disease. Comparing the means of these groups yielded the following: severe vs moderate P less than 0.005; moderate vs mild P less than 0.001; and mild vs normal P less than 0.001. Although there was some overlap between the individual groups, a clear separation existed between patients with severe and mild aortic stenosis. In addition, the group of patients in whom surgical intervention was recommended was also separated from the other subjects. When the aortic valve orifice was recorded using the M-mode technique, there was also a good correlation with the severity of the stenosis; however, the tendency of the M-mode study to overestimate severity in individual patients with calcific aortic stenosis and to underestimate severity in congenital aortic stenosis was again demonstrated. This study suggests that real-time, high resolution, cross-sectional echocardiography should be valuable in the noninvasive assessment of patients with aortic stenosis.

摘要

使用高分辨率机械扇形扫描仪,对28例连续性成年主动脉瓣狭窄患者进行实时横断面超声心动图检查。采用横断面技术,记录了这28例患者的主动脉瓣口直径。对这些相同患者进行M型超声心动图检查时,在这28例患者中只有21例(75%)能够估算出该值。在横断面研究中记录的最大主动脉瓣直径,15例重度主动脉狭窄患者平均为7.9±1.8mm(范围4 - 11mm);5例中度主动脉狭窄患者为11.6±2.3mm(范围9 - 15mm);8例轻度主动脉狭窄患者为16.9±2.0mm(范围14 - 20mm);25例无主动脉瓣疾病证据的患者为20.5±2.8mm(范围15 - 26mm)。比较这些组的均值得出以下结果:重度与中度相比P<0.005;中度与轻度相比P<0.001;轻度与正常相比P<0.001。虽然各单独组之间存在一些重叠,但重度和轻度主动脉狭窄患者之间存在明显区分。此外,建议进行手术干预的患者组也与其他受试者区分开来。当使用M型技术记录主动脉瓣口时,与狭窄严重程度也有良好的相关性;然而,再次证明M型研究在个别钙化性主动脉狭窄患者中倾向于高估严重程度,而在先天性主动脉狭窄患者中倾向于低估严重程度。本研究表明,实时、高分辨率横断面超声心动图在主动脉狭窄患者的无创评估中应具有重要价值。

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