DePace N L, Nestico P F, Kotler M N, Mintz G S, Kimbiris D, Goel I P, Glazier-Laskey E E, Ross J
Br Heart J. 1984 Jan;51(1):36-45. doi: 10.1136/hrt.51.1.36.
To assess the accuracy of echocardiography in determining the cause of aortic regurgitation M mode and cross sectional echocardiography were compared with angiography in 43 patients with predominant aortic regurgitation. Each patient had all three investigations performed during the same admission to hospital. In each instance, the cause of aortic regurgitation was confirmed at surgery or necropsy. Seventeen patients had rheumatic aortic valve disease, 13 bacterial endocarditis with a perforated or partially destroyed cusp, five a bicuspid aortic valve (four with a history of endocarditis), and eight aortic regurgitation secondary to aortic root dilatation or aneurysm. Overall sensitivity of echocardiography and aortography was 84% in determining the cause of aortic regurgitation. Thus, rheumatic valve disease and endocarditis appear to be the most common causes of severe aortic regurgitation in this hospital based population. Furthermore, echocardiography is a sensitive non-invasive technique for determining the cause of aortic regurgitation and allows differentiation of valvular from root causes of aortic regurgitation.
为评估超声心动图在确定主动脉瓣反流病因方面的准确性，对43例以主动脉瓣反流为主的患者进行了M型和横截面超声心动图检查，并与血管造影进行了比较。每位患者在同一住院期间均接受了这三项检查。在每种情况下，主动脉瓣反流的病因均在手术或尸检时得到证实。17例患者患有风湿性主动脉瓣疾病，13例患有细菌性心内膜炎且伴有尖瓣穿孔或部分破坏，5例患有二叶式主动脉瓣（4例有感染性心内膜炎病史），8例主动脉瓣反流继发于主动脉根部扩张或动脉瘤。超声心动图和主动脉造影在确定主动脉瓣反流病因方面的总体敏感性为84%。因此，在这个以医院为基础的人群中，风湿性瓣膜病和心内膜炎似乎是严重主动脉瓣反流的最常见病因。此外，超声心动图是一种用于确定主动脉瓣反流病因的敏感非侵入性技术，并且能够区分主动脉瓣反流的瓣膜性病因和根部病因。
