Stott A W, Smith J R, Hanson P, Robinson R
Clin Chim Acta. 1975 Aug 18;63(1):7-12. doi: 10.1016/0009-8981(75)90371-x.
A rapid and simple procedure is described for the concurrent determination of 4-hydroxy-3-methoxymandelic acid (HMMA) and homovanillic acid (HVA). The acids are separated by chromatography and estimated by a scanning technique. The urinary output of HMMA and HVA over 24 h from 123 normals (80 males, 43 females) gave mean values of 3.3 +/- 0.94 and 4.9 +/- 1.3 mg, respectively. There was no significant difference in the 24 hour urinary output of HMMA and HVA between the male and femal groups.
本文描述了一种快速简便的方法,用于同时测定4-羟基-3-甲氧基扁桃酸(HMMA)和高香草酸(HVA)。通过色谱法分离这些酸,并采用扫描技术进行测定。123名正常人(80名男性,43名女性)24小时尿液中HMMA和HVA的排出量,其平均值分别为3.3±0.94毫克和4.9±1.3毫克。男性组和女性组之间HMMA和HVA的24小时尿液排出量无显著差异。