Gullapalli Dakshinamurty, Phillips Lawrence H
Neuromuscular Diseases and Clinical Neurophysiology, Department of Neurology, University of Virginia, Charlottesville, Virginia 22908, USA.
Neurol Clin. 2002 Feb;20(1):59-83, vi. doi: 10.1016/s0733-8619(03)00054-9.
Sarcoidosis is multisystem granulomatous disease of unknown etiology. Although the nervous system is involved in only 5% to 16% of patients, neurosarcoidosis is one of the more serious manifestations of the disease. Cranial neuropathies are common, but involvement of the mininges or the brain or spinal cord parenchyma causes more severe morbidity. MR imaging of affected portions of the neuraxis is a very sensitive diagnostic technique. Treatment with corticosteroids is the mainstay of therapy.
结节病是一种病因不明的多系统肉芽肿性疾病。虽然仅有5%至16%的患者累及神经系统，但神经结节病是该疾病较严重的表现之一。颅神经病变很常见，但脑膜、脑或脊髓实质受累会导致更严重的发病情况。对神经轴受影响部位进行磁共振成像检查是一种非常敏感的诊断技术。皮质类固醇治疗是主要的治疗方法。
