Lostroh C P, Lee C A
Department of Microbiology and Molecular Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, Massachusetts 02115, USA.
Microbes Infect. 2001 Nov-Dec;3(14-15):1281-91. doi: 10.1016/s1286-4579(01)01488-5.
Salmonella pathogenicity island 1 (SPI1) encodes a type III secretion system that is required for virulence during the intestinal phase of infection. The expression of SPI1 genes is controlled by many global regulatory pathways that affect the expression/activity of transcriptional regulators encoded on SPI1.
沙门氏菌致病岛1(SPI1)编码一种III型分泌系统,该系统是感染肠道阶段毒力所必需的。SPI1基因的表达受许多全局调控途径控制,这些途径影响SPI1上编码的转录调节因子的表达/活性。