Sakata T, Kuwahara Y
Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Japan.
Biosci Biotechnol Biochem. 2001 Oct;65(10):2315-7. doi: 10.1271/bbb.65.2315.
The structure of a novel aromatic compound contained in the unidentified Rhizoglyhus mite (Acaridae: Astigmata) was elucidated, without its isolation, to be 3-hydroxybenzene-1,2-dicarbaldehyde (tentatively named gamma-acaridial) by a combination of GC/MS and GC/FT-IR together with knowledge of related mite compounds. The structure was confirmed by a 5-step synthesis, starting from methyl 3-hydroxybenzoate, in a 15% overall yield. The compound is widely distributed not only among Astigmata but also among Oribatida, although its biological function is obscure at present.
在未对其进行分离的情况下，通过气相色谱/质谱联用（GC/MS）和气相色谱/傅里叶变换红外光谱联用（GC/FT-IR），并结合对相关螨类化合物的了解，阐明了未鉴定的根螨（粉螨科：粉螨亚目）中所含一种新型芳香化合物的结构，确定其为3-羟基苯-1,2-二甲醛（暂定名为γ-粉螨醛）。该结构通过从3-羟基苯甲酸甲酯开始的五步合成得到证实，总产率为15%。该化合物不仅在粉螨亚目中广泛分布，在甲螨亚目中也广泛分布，尽管其目前的生物学功能尚不清楚。
