Drory Y
Harefuah. 2001 Nov;140(11):1032-7, 1117.
Numerous epidemiological studies have disclosed documented evidence that light to moderate consumption of any alcoholic beverage is associated with approximately 20% reduction in cardiovascular disease risk. This finding applies to both men and women and to healthy individuals as well as those with coronary heart disease, diabetes, hypertension, or heart failure. Nevertheless, the issue of including a recommendation for mild to moderate alcohol consumption within the routine recommendations for primary and secondary prevention of coronary heart disease is still controversial. The controversy is derived partly from methodological issues and partly from documented adverse health effects of excessive alcohol drinking. The key issue is the definition of the optimal dose of alcohol which guarantees a positive benefit-risk ratio, i.e. enjoying the benefits of alcohol without substantial risk. The accumulating scientific evidence shows that a daily consumption of less than 30 grams of alcohol for men and less than 15 grams for women is compatible with the above goal and is not associated with health risks. Therefore, for most individuals it is appropriate to recommend mild to moderate alcohol consumption as part of a healthy life style for the prevention of cardiovascular disease. Recommendations should be given on an individual basis, taking into account the patient's age, gender, physical and mental health status, personality and past drinking habits. The desirable quantity and its upper limit as well as drinking patterns should be clearly defined. All persons should be warned to avoid heavy drinking. Awareness of indications for abstinence from alcohol such as pregnancy, sport activity and the use of certain medications is highly important.
众多流行病学研究已披露有记录的证据表明,适量饮用任何酒精饮料可使心血管疾病风险降低约20%。这一发现适用于男性和女性,以及健康个体和患有冠心病、糖尿病、高血压或心力衰竭的人群。然而,在冠心病一级和二级预防的常规建议中纳入适度饮酒建议这一问题仍存在争议。争议部分源于方法学问题,部分源于过量饮酒已记录在案的不良健康影响。关键问题是保证有利的效益风险比的最佳酒精剂量的定义,即享受酒精益处而无重大风险。越来越多的科学证据表明,男性每日饮酒量少于30克、女性少于15克符合上述目标,且与健康风险无关。因此,对大多数个体而言,建议适度饮酒作为预防心血管疾病的健康生活方式的一部分是合适的。建议应根据个体情况给出,考虑患者的年龄、性别、身心健康状况、性格和既往饮酒习惯。应明确理想的饮酒量及其上限以及饮酒模式。应警告所有人避免酗酒。认识到诸如怀孕、体育活动和使用某些药物等戒酒指征非常重要。