Havertape S A, Cruz O A, Chu F C
Saint Louis University Health Sciences Center, Missouri, USA.
J Pediatr Ophthalmol Strabismus. 2001 Nov-Dec;38(6):327-30; quiz 354-5. doi: 10.3928/0191-3913-20011101-05.
The type of horizontal strabismus from loss or impairment of vision is thought to depend on patient age at the time of vision loss. Association between the age at onset of vision loss and development of esotropia vs exotropia will be determined.
Patients with a diagnosis of sensory strabismus and visual acuity of 20/40 or poorer were reviewed as well as patients with diagnoses consistent with the development of sensory strabismus. Parameters considered were age at onset of vision loss and type of strabismus. Patients were excluded if the age at onset was not clear.
Of 123 patients with sensory strabismus reviewed: 82 (67%) had unilateral vision loss; 41 (33%) had bilateral vision loss; 75 (61%) had congenital vision loss; 50 (67%) developed esotropia; 25 (33%) developed exotropia; 48 (39%) had acquired vision loss; 5 (10%) developed esotropia; and 43 (90%) developed exotropia. A significant difference was noted between age at onset and type of horizontal strabismus (X2= 37.44; P <.0001).
Of patients with congenital vision loss, 67% developed sensory esotropia and 33% developed sensory exotropia. Of those with acquired vision loss, 10% developed sensory esotropia and 90% developed sensory exotropia. Patients with congenital vision loss are significantly more likely to develop esotropia, P <.005, and those with acquired vision loss are significantly more likely to develop exotropia, P <.001.
因视力丧失或受损导致的水平斜视类型被认为取决于视力丧失时的患者年龄。将确定视力丧失发病年龄与内斜视和外斜视发展之间的关联。
对诊断为感觉性斜视且视力为20/40或更差的患者以及诊断与感觉性斜视发展一致的患者进行了回顾。所考虑的参数为视力丧失发病年龄和斜视类型。如果发病年龄不明确,则将患者排除。
在回顾的123例感觉性斜视患者中:82例(67%)有单眼视力丧失;41例(33%)有双眼视力丧失;75例(61%)有先天性视力丧失;50例(67%)发展为内斜视;25例(33%)发展为外斜视;48例(39%)有后天性视力丧失;5例(10%)发展为内斜视;43例(90%)发展为外斜视。注意到发病年龄与水平斜视类型之间存在显著差异(X2 = 37.44;P <.0001)。
在先天性视力丧失的患者中,67%发展为感觉性内斜视,33%发展为感觉性外斜视。在后天性视力丧失的患者中,10%发展为感觉性内斜视,90%发展为感觉性外斜视。先天性视力丧失的患者发生内斜视的可能性显著更高,P <.005,而后天性视力丧失的患者发生外斜视的可能性显著更高,P <.001。