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1991年至1997年泰国北部15岁以下儿童1型糖尿病的发病率。

Incidence of type 1 diabetes in children under 15 years in northern Thailand, from 1991 to 1997.

作者信息

Unachak K, Tuchinda C

机构信息

Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Thailand.

出版信息

J Med Assoc Thai. 2001 Jul;84(7):923-8.

Abstract

The annual incidence of Type 1 diabetes in children under 15 years in northern Thailand from 1991 to 1997 was a retrospective study by analyzing the data gathered from the Pediatric Endocrine Division, Faculty of Medicine, Chiang Mai University and through a mail survey to 202 hospitals in the government and private sector in northern Thailand. The response to the mail survey from 1991 to 1992 and 1993 to 1997 was 90.1 per cent and 94.5 per cent respectively. During the seven year period, 76 new cases of Type 1 diabetes were identified. The crude annual incidence ranged from 0.31-0.56/100,000 per year, with an average incidence of 0.37/100,000 per year (95% C.I. = 0.29-0.46). This very low figure had risen 2.2 fold (over 100%) from that reported in 1984. The annual incidence was relatively constant from 1991 to 1996, although there was a moderate rise in 1997 (0.56/100,000 per year). There was no statistically significant difference between the annual incidence of 1996 and 1997. It remains for further studies to confirm the trend of increased incidence. The median age of onset was 11 years, whereas, the peak age of onset occurred in the 10-14 year age group of both sexes. There was a greater incidence among female in this study. These date confirm the need to develop a national registry of Type 1 diabetes for further epidemiological research.

摘要

1991年至1997年泰国北部15岁以下儿童1型糖尿病的年发病率是一项回顾性研究,通过分析清迈大学医学院儿科内分泌科收集的数据,并对泰国北部政府和私立部门的202家医院进行邮件调查。1991年至1992年以及1993年至1997年邮件调查的回复率分别为90.1%和94.5%。在这七年期间,共确诊76例新的1型糖尿病病例。年粗发病率为每年0.31 - 0.56/10万,平均发病率为每年0.37/10万(95%置信区间 = 0.29 - 0.46)。这个极低的数字比1984年报告的数字增长了2.2倍(超过100%)。1991年至1996年年发病率相对稳定,尽管1997年有适度上升(每年0.56/10万)。1996年和1997年的年发病率之间没有统计学上的显著差异。仍需进一步研究来证实发病率上升的趋势。发病的中位年龄为11岁,而发病高峰年龄出现在10 - 14岁的男女年龄组。本研究中女性发病率更高。这些数据证实有必要建立一个全国性的1型糖尿病登记系统以进行进一步的流行病学研究。

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