Saika S, Tanaka T, Miyamoto T, Ohnishi Y
Department of Ophthalmology, Wakayama Medical University, School of Medicine, Kimiidera, Japan.
Graefes Arch Clin Exp Ophthalmol. 2001 Oct;239(10):729-32. doi: 10.1007/s004170100344.
To assess the effectiveness of surgical posterior vitreous detachment (PVD) together with gas/air tamponade in treating visual impairment from macular edema associated with branch retinal vein occlusion (BRVO-macular edema).
A cohort study was conducted. To treat visual disturbance caused by BRVO-macular edema in 19 consecutive patients at a University Hospital, phacoemulsification, intraocular lens implantation, and vitrectomy were performed, together with gas/air tamponade. Patients were followed up postoperatively for 3-18 months. Foveal structure was defined using optical coherence tomography (OCT). Preoperative visual acuity, central retinal thickness, and interval between BRVO onset and operation were compared between patients with postoperative visual improvement and those without improvement.
Ten patients recovered normal or near-normal foveal configuration, while nine patients did not. Mean postoperative visual acuity in the former group of patients was significantly higher than in the latter. Mean foveal retinal thickness decreased significantly after the operation. The interval from onset of BRVO until operation was significantly shorter in patients with improved postoperative vision than in other patients, and patients operated on within 11 months had significantly increased postoperative visual acuity.
Surgical PVD and gas/air tamponade appears effective in treating BRVO-macular edema, although relatively short duration from disease onset until operation is critical for improvement of vision. When a good postoperative foveal contour is seen, it seems to be associated with better visual outcome.
评估手术性玻璃体后脱离(PVD)联合气体/空气填塞治疗视网膜分支静脉阻塞相关性黄斑水肿(BRVO-黄斑水肿)所致视力损害的有效性。
进行了一项队列研究。为治疗某大学医院连续19例因BRVO-黄斑水肿引起视力障碍的患者,实施了超声乳化白内障吸除术、人工晶状体植入术和玻璃体切除术,并联合气体/空气填塞。术后对患者进行3至18个月的随访。使用光学相干断层扫描(OCT)定义黄斑结构。比较术后视力改善患者与未改善患者的术前视力、视网膜中央厚度以及BRVO发病至手术的间隔时间。
10例患者恢复了正常或接近正常的黄斑形态,而9例患者未恢复。前一组患者术后平均视力显著高于后一组。术后黄斑视网膜平均厚度显著降低。术后视力改善患者从BRVO发病至手术的间隔时间明显短于其他患者,且在11个月内接受手术的患者术后视力显著提高。
手术性PVD联合气体/空气填塞似乎对治疗BRVO-黄斑水肿有效,尽管从疾病发作到手术的时间相对较短对视力改善至关重要。当术后黄斑轮廓良好时,似乎与更好的视觉结果相关。