Drábek J, Halouzka R, Piskac A
Vet Med (Praha). 1979 Sep;24(9):531-42.
In two experiments, 18 pigs were given feed contaminated with aflatoxin which had been prepared by the extraction of the cultures of toxinogenic strains of the fungus Aspergillus flavus. After the ingestion of aflatoxin (AFB1) at a dose of 5.4 to 10.5 mg per kg of live weight, the pigs showed symptoms of peracute aflatoxicosis and died within 12--20 hours. After ingestion of AFB1 at a dose of 1.4 or 3.1 mg per kg live weight, the pigs suffered from acute aflatoxicosis and died within 3 to 26 days from the administration of the contaminated feed. In the cases of these experimental aflatoxicoses, clinical symptoms, haematological and biochemical changes in the blood and the patho-anatomical and histological findings in the swine organism were described.
在两项实验中，给18头猪喂食了被黄曲霉毒素污染的饲料，该饲料是通过提取黄曲霉产毒菌株的培养物制备的。猪以每千克体重5.4至10.5毫克的剂量摄入黄曲霉毒素（AFB1）后，出现了超急性黄曲霉中毒症状，并在12至20小时内死亡。猪以每千克体重1.4或3.1毫克的剂量摄入AFB1后，患上急性黄曲霉中毒，并在喂食受污染饲料后的3至26天内死亡。在这些实验性黄曲霉中毒病例中，描述了临床症状、血液中的血液学和生化变化以及猪机体的病理解剖和组织学发现。
