Parmar H, Shah J, Patwardhan V, Patankar T, Patkar D, Muzumdar D, Prasad S, Castillo M
Department of Radiology, King Edward VII Memorial Hospital, Parel, Mumbai, India.
Neuroradiology. 2001 Nov;43(11):961-7. doi: 10.1007/s002340100615.
Although intramedullary spinal cord cysticercosis (IMC) is uncommon, its presence is being increasingly recognised by magnetic resonance imaging. We studied six patients from an endemic region and present the MRI features and clinical correlation of IMC. Six patients who presented with para- or quadriplegia were studied by contrast enhanced spinal MRI. Prompted by the spinal lesions, all patients underwent brain MRI. Clinical data and laboratory studies were reviewed in all patients. Definite diagnosis was established in the form of response to drug therapy (n = 4) and histopathology (n = 2). Follow-up MRI studies of spine and brain were obtained in four patients 2 months after they started medical treatment, regardless of surgery. Five patients showed fusiform and focal enlargement of the spinal cord (cervical 2, thoracic 3). Well-defined cysts with a slightly hyperintense mural nodule were identified in five patients in Ti-weighted images (T1WI). All cysts were hyperintense on T2WI and merged with the surrounding oedema. Oedema extended one to three vertebral levels above or below the cyst. Post-contrast T1WI showed well-defined, ring enhancing lesions with smooth walls in all patients. Symptoms in all patients correlated with the level of the lesions. Brain studies demonstrated lesions in just two patients. Histopathological confirmation was obtained in two patients. Follow-up spinal MRI was normal in two patients, following 2 months of treatment while residual and smaller lesions were seen in two patients. Two patients were asymptomatic and denied follow-up MRI. MRI of spinal cysticercosis were typical of and similar to those seen in cerebral lesions in our patients and corresponded to the level of symptoms. All cysts were surrounded by oedema. Two of four patients showed residual lesions after 2 months of therapy and 33 % of patients showed concomitant intracranial lesions.
尽管脊髓髓内囊尾蚴病(IMC)并不常见,但磁共振成像对其的识别越来越多。我们研究了来自流行地区的6例患者,并呈现了IMC的MRI特征及临床相关性。对6例出现截瘫或四肢瘫的患者进行了增强脊髓MRI检查。因脊髓病变,所有患者均接受了脑部MRI检查。回顾了所有患者的临床资料和实验室检查结果。通过药物治疗反应(n = 4)和组织病理学(n = 2)确诊。4例患者在开始药物治疗2个月后,无论是否接受手术,均进行了脊柱和脑部的随访MRI检查。5例患者脊髓呈梭形和局灶性增粗(颈2、胸3)。在T1加权像(T1WI)上,5例患者可见边界清晰的囊肿,囊壁结节呈轻度高信号。所有囊肿在T2加权像(T2WI)上均为高信号,并与周围水肿融合。水肿在囊肿上方或下方延伸1至3个椎体节段。增强后T1WI显示所有患者的病变边界清晰,呈环形强化,壁光滑。所有患者的症状与病变水平相关。脑部检查仅2例患者发现病变。2例患者获得了组织病理学证实。2例患者治疗2个月后随访脊柱MRI正常,另2例患者可见残留且较小的病变。2例患者无症状,未接受随访MRI检查。脊髓囊尾蚴病的MRI表现典型,与我们患者脑部病变所见相似,且与症状水平相符。所有囊肿均被水肿包围。4例患者中有2例在治疗2个月后显示残留病变,33%的患者伴有颅内病变。