Beckman G, Beckman L
Hum Hered. 1975;25(3):172-6. doi: 10.1159/000152724.
The PGM1 and PGM3 phenotypes were examined in extracts of chorionic tissue from 97 spontaneous and 266 induced abortions. Contamination by maternal tissue or blood cells was shown to be insignificant. A positive association was found between the PGM11 and PGM13 genes. No significant differences in phenotype distributions were found between the population of spontaneously aborted fetuses and the normal fetal or adult populations. Hence it was concluded that there is no evidence so far for prenatal selection operating in the PGM1 and PGM3 polymorphisms.
对97例自然流产和266例人工流产的绒毛组织提取物进行了PGM1和PGM3表型检测。结果显示，母体组织或血细胞污染不显著。发现PGM11和PGM13基因之间存在正相关。自然流产胎儿群体与正常胎儿或成人群体在表型分布上没有显著差异。因此得出结论，目前尚无证据表明PGM1和PGM3多态性存在产前选择作用。
