Eapen V, Laker M, Anfield A, Dobbs J, Robertson M M
Faculty of Medicine and Health Sciences, United Arab Emirates University, PO Box 17666, Al Ain, United Arab Emirates.
J Psychiatry Neurosci. 2001 Nov;26(5):417-20.
Given the widely recognized genetic basis for Gilles de la Tourette syndrome (TS) and the suggestion that the putative TS gene(s) may be expressed as or associated with a variety of psychiatric illnesses, this study was undertaken to assess the prevalence of tics and TS in a psychiatric inpatient population.
Cross-sectional study.
200 consecutive adult patients who were admitted to the psychiatric wards of University College London Teaching Hospitals.
TS and related behaviours, as assessed by the comprehensive semi-structured National Hospital Interview Schedule.
None of the 200 patients had definite TS, but 2 were observed to have motor tics; 10 had a history of tics (present for less than a year), and 7 reported a family history of tics. Thus, 19 (9.5%) inpatients qualified for inclusion in a broadly defined TS diathesis. These rates are significantly lower than those reported in a similar community based epidemiological study of adolescents (p = 0.018).
Our findings do not support the theory that TS and related behaviours are over-represented among adult inpatients with psychiatric illnesses.
鉴于抽动秽语综合征(TS)广泛认可的遗传基础,以及推测的TS基因可能以多种精神疾病的形式表达或与之相关,本研究旨在评估精神科住院患者中抽动和TS的患病率。
横断面研究。
200名连续入住伦敦大学学院教学医院精神科病房的成年患者。
通过全面的半结构化国家医院访谈时间表评估TS及相关行为。
200名患者中无一例确诊为TS,但观察到2例有运动性抽动;10例有抽动病史(持续时间少于1年),7例报告有抽动家族史。因此,19例(9.5%)住院患者符合广义TS素质的纳入标准。这些比率显著低于在类似的基于社区的青少年流行病学研究中报告的比率(p = 0.018)。
我们的研究结果不支持TS及相关行为在成年精神科住院患者中过度存在的理论。