Fisher S D, Lipshultz S E
Department of Medicine, University of Rochester Medical Center and University of Rochester School of Medicine and Dentistry, New York 14642, USA.
Ann N Y Acad Sci. 2001 Nov;946:13-22. doi: 10.1111/j.1749-6632.2001.tb03900.x.
The epidemiology of cardiac complications related to HIV including cardiomyopathy, increased left ventricular mass, myocarditis, pericardial effusion, endocarditis, and malignancy are discussed. A large number of HIV-infected individuals will present with cardiac complications in the next decade as chronic viral infection, co-infections, drug therapy, and immunosuppression affect the heart. Understanding the nature and course of cardiac illness related to HIV infection will allow appropriate monitoring, early intervention and therapy, and will provide a baseline to evaluate the effects of new therapeutic regimens such as highly active antiretroviral therapy on the cardiovascular system.
本文讨论了与人类免疫缺陷病毒(HIV)相关的心脏并发症的流行病学,包括心肌病、左心室质量增加、心肌炎、心包积液、心内膜炎和恶性肿瘤。在未来十年中,大量感染HIV的个体将出现心脏并发症,因为慢性病毒感染、合并感染、药物治疗和免疫抑制都会影响心脏。了解与HIV感染相关的心脏疾病的性质和病程,将有助于进行适当的监测、早期干预和治疗,并为评估高效抗逆转录病毒疗法等新治疗方案对心血管系统的影响提供基线。