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消灭脊髓灰质炎的设想方案。

A scenario for polio eradication.

作者信息

Arita I

机构信息

Agency for Cooperation in International Health (ACIH), Kumamoto, Japan.

出版信息

Dev Biol (Basel). 2001;105:33-40.

Abstract

Polio eradication has entered the phase operating in the Asian sub-continent and in sub-Saharan Africa, where polio is still endemic in 30 countries. These countries are apparently most resistant to the eradication effort. The WHO polio panel held in May, in Geneva, discussed a scenario to stop transmission by 2002 and thereafter three years for certification. This paper discusses the scenario based on experience with smallpox eradication from the viewpoint of impact of population density on immunisation. The programme in the Indian sub-continent, which has the world's highest population density, may require a more rigorous surveillance-containment type strategy than that in sub-Saharan Africa which, with its lower density of population in many countries, may be relatively susceptible to the eradication effort. However, countries with higher population density and/or with political trouble may pose substantial difficulties. Also briefly discussed are measures to be taken after interruption of polio transmission world-wide. These still require intensive studies. The goal is foreseeable and with intensified mobilisation of global resources.

摘要

脊髓灰质炎根除工作已进入在亚洲次大陆和撒哈拉以南非洲开展行动的阶段,在这些地区,仍有30个国家存在脊髓灰质炎地方流行。这些国家显然对根除工作最具抵抗力。5月在日内瓦举行的世卫组织脊髓灰质炎专家小组会议讨论了到2002年停止传播并在其后三年进行认证的设想。本文从人口密度对免疫接种的影响角度,根据天花根除经验讨论了这一设想。印度次大陆的项目拥有世界最高的人口密度,可能需要比撒哈拉以南非洲更为严格的监测-遏制型战略,撒哈拉以南非洲许多国家人口密度较低,可能相对容易开展根除工作。然而,人口密度较高和/或存在政治问题的国家可能会带来重大困难。还简要讨论了全球脊髓灰质炎传播中断后应采取的措施。这些措施仍需要深入研究。目标是可预见的,并且需要加强全球资源的动员。

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