Graczyk T K, Mudakikwa A B, Cranfield M R, Eilenberger U
Harry W. Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Parasitol Res. 2001 Dec;87(12):1024-8. doi: 10.1007/s004360100489.
To facilitate ecotourism and behavioral research, free-ranging mountain gorillas (Gorilla gorilla beringei) have been habituated to humans. During routine health monitoring, five juvenile gorillas were observed with active crusted dermatitis and alopecia. Papular and vesicular lesions and crusts with papular eruption and oozing were numerous and disseminated over the body of one gorilla with a confirmed infestation of scabies. In this gorilla, the hyperkeratotic crusts were loose and thick with a flaky and scaly appearance. Histologically, the epidermis was thickened, displayed hyperkeratosis and was infiltrated with lymphocytes and neutrophils. Examination of skin scraping yielded a positive identification of adults and eggs of Sarcoptes scabiei mites. The gorillas were treated with ivermectin, 200 mg kg(-1). As S. scabiei mites can cross-infect various mammalian species causing self-limiting dermatitis, these ectoparasites can be propagated in the habitats shared by gorillas, people, and livestock, and therefore they represent an anthropozoonotic threat.
为促进生态旅游和行为研究，自由放养的山地大猩猩（Gorilla gorilla beringei）已习惯与人类接触。在常规健康监测期间，观察到五只幼年大猩猩患有活动性结痂性皮炎和脱毛症。一只确诊感染疥疮的大猩猩身上出现大量丘疹、水疱性病变以及伴有丘疹疹和渗出的结痂，且遍布全身。在这只大猩猩身上，角化过度的结痂疏松且厚实，外观呈片状和鳞片状。组织学检查显示，表皮增厚，出现角化过度，并有淋巴细胞和中性粒细胞浸润。皮肤刮片检查确诊为疥螨成虫和虫卵。这些大猩猩接受了200毫克/千克的伊维菌素治疗。由于疥螨可交叉感染各种哺乳动物物种，引发自限性皮肤炎，这些体外寄生虫可在大猩猩、人类和牲畜共有的栖息地中传播，因此构成人兽共患病威胁。
