卢旺达火山国家公园中习惯与人类接触的山地大猩猩（山地大猩猩指名亚种）感染肝毛细线虫（线虫纲）情况。

Capillaria hepatica (Nematoda) infections in human-habituated mountain gorillas (Gorilla gorilla beringei) of the Parc National de Volcans, Rwanda.

作者信息

Graczyk T K, Lowenstine L J, Cranfield M R

机构信息

Department of Molecular Microbiology and Immunology, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA.

出版信息

J Parasitol. 1999 Dec;85(6):1168-70.

PMID:10647051

Abstract

Habituation to humans of free-ranging populations of endangered mountain gorillas (Gorilla gorilla beringei) raised concern of anthropozoonotic transmission of parasitic helminths and protozoans. Examinations of liver tissue of 19 gorillas found dead in the Parc National de Volcans, Rwanda, revealed 10 cases of hepatic nematodiasis due to Capillaria hepatica. Identifiable C. hepatica eggs were present in the liver of 4 gorillas (3 juveniles, 1 adult), and nematode cross-sections were found in 1 juvenile gorilla. Six other adult gorillas had areas of periportal and subcapsular fibrosis with calcified eggs. Histologically, the lesions surrounded by the areas of mild inflammatory reaction were characterized by subcapsular, periportal foci of fibrosis in which were embedded numerous C. hepatica eggs. Control of hepatic capillariasis in the remaining populations of mountain gorillas should be focused on eradication or control of populations of rodent pests (i.e., mice and rats) that sustain the reservoir of C. hepatica in habitats shared by gorillas and humans.

摘要

濒危山地大猩猩（Gorilla gorilla beringei）自由放养种群对人类的习惯化引发了对寄生虫和原生动物人兽共患病传播的担忧。对在卢旺达火山国家公园死亡的19只大猩猩的肝脏组织进行检查后发现，有10例因肝毛细线虫（Capillaria hepatica）导致的肝线虫病。在4只大猩猩（3只幼年，1只成年）的肝脏中发现了可识别的肝毛细线虫卵，在1只幼年大猩猩中发现了线虫横切面。另外6只成年大猩猩有门静脉周围和包膜下纤维化区域，伴有钙化卵。组织学上，病变周围有轻度炎症反应区域，其特征是包膜下、门静脉周围的纤维化病灶，其中嵌入了大量肝毛细线虫卵。对其余山地大猩猩种群肝毛细线虫病的控制应集中于根除或控制啮齿类害虫（即小鼠和大鼠）种群，这些害虫在大猩猩和人类共享的栖息地中维持着肝毛细线虫的宿主。