Crofford L J
Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, Michigan, USA.
Gastroenterol Clin North Am. 2001 Dec;30(4):863-76. doi: 10.1016/s0889-8553(05)70217-x.
PGs are important mediators of normal physiology, response to injury, and pathologic processes. Dissecting these biochemical and molecular pathways allows development of therapeutic agents that can be [figure: see text] applied to specific clinical situations, while preserving PGs that play a role in normal physiology.
前列腺素是正常生理、损伤反应及病理过程的重要介质。剖析这些生化和分子途径有助于开发可应用于特定临床情况的治疗药物,同时保留在正常生理中起作用的前列腺素。