Ok M, Sen I, Turgut K, Irmak K
Department of Internal Medicine, Faculty of Veterinary Medicine, University of Selcuk, Konya, Turkey.
J Vet Med A Physiol Pathol Clin Med. 2001 Nov;48(9):563-8. doi: 10.1046/j.1439-0442.2001.00389.x.
The present study was designed to evaluate the usefulness of plasma gastrin determinations as a diagnostic aid and to review the clinical and haematological findings in cattle with bleeding abomasal ulcers. Twenty-nine cows with bleeding abomasal ulcers and six healthy cows were used. Clinical and laboratory examinations, including plasma gastrin levels, were performed. Anorexia, depression, dark-coloured to black faeces, pale mucous membranes, abdominal pain, moderate tachycardia and tachypnoca were the most pronounced clinical symptoms in the cattle with bleeding abomasal ulcers. Plasma gastrin concentration was significantly higher (P < 0.05) in the cattle with bleeding abomasal ulcers than in healthy cows. The mean plasma gastrin concentration in healthy cattle was 103.2 pg/ml, while the mean plasma gastrin concentrations in cattle with bleeding abomasal ulcers were found to be 213.6 pg/ml. Haemoglobin levels, packed cell volume, total white blood cell count and mean corpuscular volume were significantly lower (P < 0.05) in the cows with bleeding abomasal ulcer than in the healthy cattle. The results of this study show that measurement of plasma gastrin can be useful in the diagnosis of bleeding abomasal ulcers in cattle.
本研究旨在评估血浆胃泌素测定作为一种诊断辅助手段的实用性，并回顾患有出血性皱胃溃疡的牛的临床和血液学检查结果。使用了29头患有出血性皱胃溃疡的母牛和6头健康母牛。进行了包括血浆胃泌素水平在内的临床和实验室检查。厌食、抑郁、深色至黑色粪便、黏膜苍白、腹痛、中度心动过速和呼吸急促是患有出血性皱胃溃疡的牛最明显的临床症状。患有出血性皱胃溃疡的牛的血浆胃泌素浓度显著高于健康母牛（P < 0.05）。健康牛的平均血浆胃泌素浓度为103.2 pg/ml，而患有出血性皱胃溃疡的牛的平均血浆胃泌素浓度为213.6 pg/ml。患有出血性皱胃溃疡的母牛的血红蛋白水平、红细胞压积、白细胞总数和平均红细胞体积显著低于健康牛（P < 0.05）。本研究结果表明，测定血浆胃泌素对诊断牛的出血性皱胃溃疡可能有用。
