Cutler S J, Hodgson L G
Department of Sociology, University of Vermont, Burlington, USA.
Am J Alzheimers Dis Other Demen. 2001 Nov-Dec;16(6):335-43. doi: 10.1177/153331750101600604.
We examine correlates of personal concerns about developing Alzheimer's disease (AD) among (1) adult children, 40 to 60 years of age, who have a living parent with a diagnosis of probable AD (N = 108), and (2) a matched comparison group of persons with no parental history of AD (N = 150). Using stepwise regression, predictors measuring subjective perceptions of memory functioning, overall family history of AD, knowledge of AD, and sociodemographic characteristics were entered into models for the total sample and each of the subsamples. The results indicate that worries about memory functioning play a consistent role in personal concerns about developing AD across both groups, but that additional pathways to personal concerns differ among individuals having and not having a parent with AD.
我们研究了两组人群中对患阿尔茨海默病(AD)的个人担忧的相关因素:(1)40至60岁的成年子女,其在世父母被诊断为可能患有AD(N = 108);(2)一个匹配的对照组,其成员无AD家族病史(N = 150)。使用逐步回归分析,将测量记忆功能主观认知、AD家族病史、AD知识以及社会人口学特征的预测变量纳入总样本和每个子样本的模型中。结果表明,对记忆功能的担忧在两组人群对患AD的个人担忧中都发挥着持续作用,但有AD父母和没有AD父母的个体,导致个人担忧的其他途径有所不同。