Bahlo M, Griffiths R C
The Walter and Eliza Hall Institute of Medical Research, Genetics and Bioinformatics Group, Post Office, Royal Melbourne Hospital, Parkville, VIC 3050, Australia.
J Math Biol. 2001 Nov;43(5):397-410. doi: 10.1007/s002850100104.
In this paper a new form of the solution for the Laplace transform and moments of the distribution of the waiting time for two genes to coalescence is presented. The two genes are sampled from a subdivided population where migration rates between populations are constant in time. Equal subpopulation size is not assumed. For the special case of an island model with equal migration rates between islands, the Laplace transform of the coalescence time and the first and second moments are found explicitly. The new form of the solutions allows numerical calculation. The connection of how the results relate to a panmictic population when migration rates are large is illustrated using strong-migration-limit theory.
本文给出了两个基因合并等待时间分布的拉普拉斯变换和矩的一种新形式的解。这两个基因是从一个细分种群中抽样得到的,种群间的迁移率随时间恒定。不假设亚种群大小相等。对于岛屿间迁移率相等的岛屿模型的特殊情况,明确求出了合并时间的拉普拉斯变换以及一阶和二阶矩。解的新形式便于进行数值计算。利用强迁移极限理论说明了当迁移率很大时结果与随机交配种群的关系。