Joly M, Lefebvre H, Kuhn J M
IFRMP, Université de Rouen, Service d'endocrinologie et maladies métaboliques CHU Rouen 76230 Bois-Guillaume.
Rev Prat. 1998 Apr 1;48(7):724-30.
Adrenal insufficiency can be either primitive as the result of a destruction of the glands or secondary to a corticotropic failure. Adrenal insufficiency can appear as an acute event or in contrast arise progressively. An acute adrenal insufficiency can occur any time and threatens the vital prognosis. It should be prevented by adapted treatment and education of the patient. The treatment of adrenal insufficiency includes substitutive doses of mineralo and/or glucocorticoids and, as often as possible, etiologic therapy. For this reason, as soon as the diagnosis of adrenal insufficiency has been done, a main point is to determine the cause of the endocrine failure. Indeed, some diseases responsible for adrenal deficiency, among a progressively extending list of etiologic factors, can benefit for a specific treatment.
肾上腺功能不全可原发性地由于腺体破坏所致，或继发性于促肾上腺皮质激素分泌不足。肾上腺功能不全可表现为急性事件，或者相反，呈进行性发生。急性肾上腺功能不全可在任何时候发生，并危及生命预后。应通过适当的治疗和对患者的教育来预防。肾上腺功能不全的治疗包括给予替代剂量的盐皮质激素和/或糖皮质激素，并尽可能进行病因治疗。因此，一旦诊断出肾上腺功能不全，关键一点就是确定内分泌功能衰竭的病因。事实上，在病因因素不断增加的清单中，一些导致肾上腺功能不全的疾病可从特定治疗中获益。
