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[血管紧张素转换酶抑制剂和氯沙坦对肺结核合并慢性心力衰竭患者生活质量的影响]

[Effects of angiotensin-converting enzyme inhibitors and cosaar on quality of life of patients with pulmonary tuberculosis and chronic heart failure].

作者信息

Ditiatkov A E, Tikhonov V A, Radzevich A E

出版信息

Probl Tuberk. 2001(8):37-9.

PMID:11767390
Abstract

Two and thirty four patients with pulmonary tuberculosis complicated with chronic heart failure (CHF) were examined to study life quality (LQ) and its changes due to hemodynamic correction. LQ was assessed by the Minnesota Life Heart Failure Quality questionnaire filled in by patients before and after treatment of CHF with angiotensin-converting enzyme inhibitors (captopril, ramipril, prestarium) and an angiotensin II-receptor blocker (cosaar) given for 1.5-2 months during chemotherapy for tuberculosis. In patients with pulmonary tuberculosis complicated by CHF, LQ was found to be related to the degree of hemodynamic disorders and to significantly improves with complex treatment of a tuberculous process and with correction of hemodynamic disorders.

摘要

对234例肺结核合并慢性心力衰竭(CHF)患者进行检查,以研究生活质量(LQ)及其因血液动力学纠正而发生的变化。LQ通过明尼苏达心力衰竭生活质量问卷进行评估,该问卷由患者在使用血管紧张素转换酶抑制剂(卡托普利、雷米普利、培哚普利)和血管紧张素II受体阻滞剂(氯沙坦)治疗CHF前后填写,这些药物在肺结核化疗期间给药1.5 - 2个月。在肺结核合并CHF的患者中,发现LQ与血液动力学紊乱程度相关,并且在结核病程的综合治疗和血液动力学紊乱的纠正后显著改善。

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