Radzevich A E, Ditiatkov A E, Tikhonov V A
Probl Tuberk. 2001(5):16-9.
The renin-angiotension-aldosterone system (RAAS) was studied in 93 patients with pulmonary tuberculosis complicated by chronic heart failure (CHF). Radioimmunoassay was used to determine plasma renin activity (PRA) and serum angiotensin I and aldesterone levels. There was higher RAAS activity, as shown by elevated PRA. RAAS activity decreased during CHF treatment with angiotension-converting enzyme inhibitors (captopril, ramipril, prestarium) and an angiotensin II-receptor blocker (cosaar), which is indicative of the efficiency of CHF treatment.
对93例合并慢性心力衰竭（CHF）的肺结核患者的肾素 - 血管紧张素 - 醛固酮系统（RAAS）进行了研究。采用放射免疫分析法测定血浆肾素活性（PRA）以及血清血管紧张素I和醛固酮水平。PRA升高表明RAAS活性较高。在用血管紧张素转换酶抑制剂（卡托普利、雷米普利、培哚普利）和血管紧张素II受体阻滞剂（氯沙坦）治疗CHF期间，RAAS活性降低，这表明CHF治疗有效。
