Liu Y, Qin S Z, Li W B
Aviation & Diving Medical Center, Naval General Hospital, Beijing, China.
Space Med Med Eng (Beijing). 2000 Dec;13(6):414-6.
Objective. To study the effect of acute moderate hypoxia on plasma lactic acid (LA) and lactic dehydrogenase (LDH) content in pilots. Method. Concentrations of plasma LA and LDH were measured by colorimetry in 16 healthy male pilots in the early morning (6:00 a.m.), following acute moderate hypoxic exposure (10:00 a.m.) and 6 hours after returned to the ground (4:00 p.m.). 16 healthy male ground people served as control group, and their plasma LA and LDH contents were assayed at corresponding time. Result. Plasma LA after moderate hypoxic exposure in the pilot group was significantly higher than that at 6:00 a.m., 4:00 p.m., and control group (P < 0.01). While the content at 6:00 a.m., 4:00 p.m. in pilot group was not significantly different from the control group (P > 0.05). The content of plasma LDH after moderate hypoxic exposure in the pilot group was not significantly higher than that at 6:00 a.m., 4:00 p.m., and control group (P > 0.05). Conclusion. Acute moderate hypoxia can make the plasma LA content increase in pilots, and reach to the normal level within 6 h. While the LDH content has no significantly change.
目的。研究急性中度缺氧对飞行员血浆乳酸（LA）和乳酸脱氢酶（LDH）含量的影响。方法。采用比色法测定16名健康男性飞行员清晨（上午6:00）、急性中度缺氧暴露后（上午10:00）及返回地面6小时后（下午4:00）血浆LA和LDH的浓度。16名健康男性地面人员作为对照组，在相应时间测定其血浆LA和LDH含量。结果。飞行员组中度缺氧暴露后血浆LA显著高于上午6:00、下午4:00时及对照组（P<0.01）。而飞行员组上午6:00、下午4:00时含量与对照组差异无统计学意义（P>0.05）。飞行员组中度缺氧暴露后血浆LDH含量高于上午6:00、下午4:00时及对照组，但差异无统计学意义（P>0.05）。结论。急性中度缺氧可使飞行员血浆LA含量升高，并在6小时内恢复至正常水平。而LDH含量无明显变化。
