Ahmed J, Zaman M M, Rouf M A, Hassan M M, Zareen S
National Centre for Control of Rheumatic Fever and Heart Diseases, Sher-e-Bangla Nagar, Dhaka, Bangladesh.
J Epidemiol. 2001 Nov;11(6):263-5. doi: 10.2188/jea.11.263.
The reference value of immunoglobulins (Igs) should be known for a population concerned because it is influenced by many clinical and local conditions. As yet the reference value of the Igs have not been determined in Bangladeshi children. This study determined the reference value of Igs in apparently healthy 261 rural Bangladeshi primary school children (aged 5 to 14 years, mean 9.3 years). IgG, IgM and IgA were determined by an auto-analyzer. The mean (standard deviation) value of IgG was 1728 (344) mg/dl. The corresponding values for IgM and IgA were 200 (88) and 163 (63) mg/dl, respectively. The 95% reference value calculation in all subjects showed that the range for IgG was 1103 to 2524, IgM was 92 to 390, and IgA was 72 to 325 mg/dl. These values could be used to evaluate Ig status in children with a variety of clinical conditions.
由于免疫球蛋白(Igs)的参考值受多种临床和局部条件影响,因此应了解特定人群的免疫球蛋白参考值。目前,孟加拉国儿童的免疫球蛋白参考值尚未确定。本研究测定了261名表面健康的孟加拉国农村小学生(年龄5至14岁,平均9.3岁)的免疫球蛋白参考值。通过自动分析仪测定IgG、IgM和IgA。IgG的平均(标准差)值为1728(344)mg/dl。IgM和IgA的相应值分别为200(88)和163(63)mg/dl。所有受试者的95%参考值计算结果显示,IgG的范围为1103至2524,IgM为92至390,IgA为72至325mg/dl。这些值可用于评估患有各种临床病症儿童的免疫球蛋白状态。