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甲状腺癌手术后的喉返神经麻痹:一个喉科学和外科学问题。

Recurrent laryngeal nerve palsy after thyroid cancer surgery: a laryngological and surgical problem.

作者信息

Misiolek M, Waler J, Namyslowski G, Kucharzewski M, Podwinski A, Czecior E

机构信息

II ENT Department Silesian Medical University, Zabrze, Poland.

出版信息

Eur Arch Otorhinolaryngol. 2001 Nov;258(9):460-2. doi: 10.1007/s004050100370.

Abstract

Recurrent laryngeal nerve paralysis is one of the most frequent complications after thyroid surgery due to goiter and cancers. A higher probability of this complication occurs after secondary procedure of the thyroid and in malignant cases. The symptoms may differ and depend on many factors. Generally, patients need careful ENT and surgical care including diagnosis and treatment. Four hundred and sixty-six patients who underwent thyroid operation due to cancer were analyzed. The group was composed of 227 papillary carcinoma, 87 follicular carcinoma, 51 medullary carcinoma, and 101 anaplastic carcinoma. Two hundred and fifty-three total thyroidectomies, 82 lobectomies and subtotal second lobe operations, 91 subtotal thyroidectomies, and 40 biopsies (wedge resections) were performed. In all 426 total and subtotal thyroidectomies an attempt to identify the recurrent laryngeal nerves was carried out. For 360 patients (77%) the surgical procedure was primary and for 106 patients (23%) the operation was secondary. Preoperative and postoperative laryngoscopic examinations were performed in all patients. Every patient with palsy underwent special laryngological procedures if needed (tracheotomy, phoniatric rehabilitation, conservative treatment and surgery in lack of improvement). The rate of postoperative vocal cord paralysis was 4.7%. The permanent palsy rate was 3.5%. In 1.2% recovery was observed. Of the 4.7% palsy rate, 3.2% concerned unilateral palsy and 1.5% bilateral pathology. Using the chi2 test, no significant differences between the rate of unilateral and bilateral paralysis and between temporary and permanent paralysis were found. On the basis of our material and results, identification the recurrent laryngeal nerves should be mandatory at surgery, thereby avoiding paralysis. Special laryngological procedures and surgical care from the beginning of paralysis are necessary for patients with vocal cord palsy. It allows to diagnose and treat patients with quite good results.

摘要

喉返神经麻痹是甲状腺肿和甲状腺癌手术后最常见的并发症之一。在甲状腺二次手术和恶性病例中,出现这种并发症的可能性更高。症状可能有所不同,且取决于多种因素。一般来说,患者需要耳鼻喉科和外科的精心护理,包括诊断和治疗。对466例因癌症接受甲状腺手术的患者进行了分析。该组包括227例乳头状癌、87例滤泡状癌、51例髓样癌和101例未分化癌。共进行了253例全甲状腺切除术、82例叶切除术和次全第二叶手术、91例次全甲状腺切除术以及40例活检(楔形切除术)。在所有426例全甲状腺切除术和次全甲状腺切除术中,均尝试识别喉返神经。360例患者(77%)的手术为初次手术,106例患者(23%)的手术为二次手术。所有患者均进行了术前和术后喉镜检查。每例出现麻痹的患者如有需要均接受了特殊的喉科手术(气管切开术、嗓音康复治疗、保守治疗以及在无改善情况下进行手术)。术后声带麻痹发生率为4.7%。永久性麻痹发生率为3.5%。观察到1.2%的患者恢复。在4.7%的麻痹发生率中,3.2%为单侧麻痹,1.5%为双侧病变。使用卡方检验,未发现单侧和双侧麻痹发生率以及暂时性和永久性麻痹发生率之间存在显著差异。根据我们的资料和结果,手术中必须识别喉返神经,从而避免麻痹。对于声带麻痹患者,从麻痹开始就进行特殊的喉科手术和外科护理是必要的。这有助于对患者进行诊断和治疗,并取得相当好的效果。

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