Fleischman D A, Monti L A, Dwornik L M, Moro T T, Bennett D A, Gabrieli J D
Rush-Presbyterian-St Luke's Medical Center, Department of Neurological Sciences, Chicago, Illinois, USA.
J Int Neuropsychol Soc. 2001 Nov;7(7):785-94.
This study examined the distinction between identification and production processes in repetition priming for 16 patients with Alzheimer's disease (AD) and 16 healthy old control participants (NC). Words were read in three study phases. In three test phases, participants (1) reread studied words, along with unstudied words, in a word-naming task (identification priming); (2) completed 3-letter stems of studied and unstudied words into words in a word-stem completion task (production priming); and (3) answered yes or no to having read studied and unstudied words in a recognition task (explicit memory). Explicit memory and word-stem completion priming were impaired in the AD group compared to the NC group. After correcting for baseline slowing, word-naming priming magnitude did not differ between the groups. The results suggest that the distinction between production and identification processes has promise for explaining the pattern of preservation and failure of repetition priming in AD.
本研究考察了16名阿尔茨海默病(AD)患者和16名健康老年对照参与者(NC)在重复启动中识别与生成过程的差异。单词在三个学习阶段被阅读。在三个测试阶段,参与者:(1)在单词命名任务(识别启动)中重读学习过的单词以及未学习过的单词;(2)在词干补全任务(生成启动)中将学习过和未学习过的单词的3字母词干补全为单词;(3)在识别任务(外显记忆)中对是否阅读过学习过和未学习过的单词回答“是”或“否”。与NC组相比,AD组的外显记忆和词干补全启动受损。在对基线减慢进行校正后,两组之间的单词命名启动幅度没有差异。结果表明,生成与识别过程之间的差异有望解释AD中重复启动的保留和失败模式。