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蟾蜍对颈动脉压力升高的压力和心率反应。

Pressure and heart rate responses to raised carotid pressure in the toad.

作者信息

Segura E T

出版信息

Am J Physiol. 1979 Dec;237(6):H639-43. doi: 10.1152/ajpheart.1979.237.6.H639.

DOI:10.1152/ajpheart.1979.237.6.H639
PMID:117717
Abstract

Neither transient nor steady occlusion of the bilateral carotid arterial trunks had noticeable effects on blood pressure or heart rate of the toad Bufo arenarum Hensel. Distension of isolated carotid labyrinths had no circulatory effects, whereas distension of unisolated carotid trunks by fluid infusion caused an increase in blood pressure proportional to the applied pressure. A simultaneous tachycardia was recorded. These circulatory effects seem to depend on the venous return to the heart because carotid distension was followed by a proportional rise in right atrial pressure. Consequently infusion of small volumes of saline into the right atrium also promoted tachycardia and hypertension. These responses seem not to depend on central nervous mechanisms because they persisted after complete deafferentation or removal of the bulbomesencephalic centers.

摘要

双侧颈动脉干的短暂或持续闭塞对蟾蜍Bufo arenarum Hensel的血压或心率均无明显影响。分离的颈动脉迷路扩张对循环无影响,而通过液体输注使未分离的颈动脉干扩张则导致血压升高,升高幅度与施加的压力成正比。同时记录到心动过速。这些循环效应似乎取决于心脏的静脉回流,因为颈动脉扩张后右心房压力会成比例升高。因此,向右心房输注少量生理盐水也会促进心动过速和高血压。这些反应似乎不依赖于中枢神经机制,因为在完全去传入神经或切除延髓脑桥中枢后这些反应仍然存在。

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