Novel 1,4-benzodiazepines from acylnitroso-derived hetero-Diels-Alder cycloadducts.
作者信息
Surman Matthew D, Mulvihill Mark J, Miller Marvin J
机构信息
Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, USA.
出版信息
Org Lett. 2002 Jan 10;4(1):139-41. doi: 10.1021/ol017036w.
PMID:11772110
Abstract
[reaction: see text] N(4)-Hydroxy-1,4-benzodiazepines were synthesized in a single step from synthetically versatile acylnitroso-derived hetero-Diels-Alder cycloadducts. The efficiency of this transformation was found to be dependent on the NH pK(a) of the cycloadduct sulfonamide.
摘要
Zotero 插件