Tange Rinze A, Schimanski Goesta, van Lange Jeroen W L, Grolman Wilko, Zuur Lot C
Department of Otorhinolaryngology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Auris Nasus Larynx. 2002 Jan;29(1):7-10. doi: 10.1016/s0385-8146(01)00106-7.
to determine the occurrence of the unusual side effect of a reparative granuloma after the implantation of a pure gold piston in cases of otosclerosis.
a retrospective case review study of 475 stapes operations with a pure gold piston.
Department of Otorhinolaryngology of the University of Amsterdam, The Netherlands and the HNO clinic in Luenen (Brambauer) in Germany.
four hundred and seventy five patients (328 women, 147 men, average age: 45.2 years), who clinically and per-operatively had otosclerosis, underwent a stapedotomy using a pure gold piston prosthesis. Therapeutic intervention: in cases of suspicion of a reparative granulomas or those cases that did not have improvement of the hearing after the stapedotomy, a re-operation by transcanal approach was performed.
in seven cases a reparative granuloma was diagnosed by this revision surgery. The postoperative incidence of these granulomas following stapedotomy using the pure gold piston turned out to be 1.5%.
reparative granulomas can occur after stapedotomy with a pure gold stapes piston although the incidence is low. The role of grafting material to seal the oval window niche and the treatment of these reparative granulomas following stapes surgery are discussed.
确定在耳硬化症病例中植入纯金活塞后出现修复性肉芽肿这种异常副作用的情况。
对475例使用纯金活塞的镫骨手术进行回顾性病例研究。
荷兰阿姆斯特丹大学耳鼻咽喉科以及德国吕嫩（布兰鲍尔）的HNO诊所。
475例患者（328名女性，147名男性，平均年龄：45.2岁），临床和手术中诊断为耳硬化症，接受了使用纯金活塞假体的镫骨切除术。治疗干预：对于怀疑有修复性肉芽肿的病例或镫骨切除术后听力未改善的病例，采用经耳道入路进行再次手术。
在7例病例中，通过此次翻修手术诊断出修复性肉芽肿。使用纯金活塞进行镫骨切除术后这些肉芽肿的术后发生率为1.5%。
使用纯金镫骨活塞进行镫骨切除术后可出现修复性肉芽肿，尽管发生率较低。讨论了用于封闭卵圆窗龛的移植材料的作用以及镫骨手术后这些修复性肉芽肿的治疗方法。
