某些2-杂芳基-α-甲基-5-苯并恶唑乙酸的合成与抗炎活性
Synthesis and antiinflammatory activity of some 2-heteroaryl-alpha-methyl-5-benzoxazoleacetic acids.
作者信息
Dunwell D W, Evans D, Hicks T A
出版信息
J Med Chem. 1975 Nov;18(11):1158-9. doi: 10.1021/jm00245a026.
PMID:1177263
Abstract
The syntheses of eight of the title compounds are described. The compounds possessed activity comparable with that of the previously tested 2-substituted phenyl analogs in the carrageenan-induced rat paw edema test.
摘要
描述了八种标题化合物的合成。在角叉菜胶诱导的大鼠足爪水肿试验中，这些化合物具有与先前测试的2-取代苯基类似物相当的活性。
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