Evans D, Smith C E, Williamson W R
J Med Chem. 1977 Jan;20(1):169-71. doi: 10.1021/jm00211a039.
4- and 7-benzoxazoleacetic and alpha-methylacetic acids substituted in the 2 position with phenyl and substituted phenyl groups have been synthesized and tested on the carrageenan-induced rat paw edema assay. The only compound found to have significant activity, albeit of a low order, was 2-phenyl-alpha-methyl-7-benzoxazoleacetic acid.
已合成了在2位被苯基和取代苯基取代的4-和7-苯并恶唑乙酸及α-甲基乙酸，并在角叉菜胶诱导的大鼠足爪水肿试验中进行了测试。唯一被发现具有显著活性（尽管活性较低）的化合物是2-苯基-α-甲基-7-苯并恶唑乙酸。
